Showing posts with label Withdrawal. Show all posts
Showing posts with label Withdrawal. Show all posts

Thursday, February 5, 2015

What You Need to Know about Citalopram Withdrawal




When taking anti - depressants such as Citalopram, patients must not discontinue use without the advice of a physician. Anti - depressants are very pusillanimous medications. You take them to feel better. But when you stop them abruptly and without proper subordination, your initial symptoms can get worse.



So why does this happen? Why do you experience unpleasant withdrawal symptoms from a drug that is supposed to be safe and effective? This is owing to drugs are unnatural. They change the general biochemical processes of the body to accommodate their effects.



Citalopram Withdrawal



Citalopram is a selective serotonin reuptake inhibitor indicated for the treatment of depression. It acts by blocking the reuptake of serotonin in the synapses to prolong its effects and improve humour. Serotonin is a neurotransmitter or chemical in the brain which helps produce feel - good feelings that counter depression.



Normally, serotonin has to be reuptaken so that the nerve cell can use it again. It undergoes a conservative process. But with the use of citalopram, this cherished neurotransmitter is forced to run on in the nerve synapses. When it stays there, it is afflicted down into its metabolites until there is no more serotonin empty to be taken up.



With the process of conservation disastrous down, you will likely suffer from overstimulation, sleeplessness, and worsening of depression and anxiety symptoms. This is being you are now completely serotonin deficient. With inhibitory serotonin just now exhausted, your body now relies on your medication to help regulate your mood.



Here are the most common citalopram withdrawal symptoms.



1. General Withdrawal Symptoms of Citalopram Use



Flu - like symptoms occur when citalopram is discarded. The body becomes ever sensitive to substances in the air, medications or food causing itching, sneezing, skin rashes, forage fever, and nausea or vomiting. You may also feel some discomfort inside your chest. This is caused by not having enough supply of oxygen to your heart due to the narrowing of your blood vessels. Abnormal swelling in your ankles, feet, fingers, and hands may be also experienced. The loss of standard strength and a physically weak feature are also included.



2. Citalopram Withdrawal Symptoms Involving the Nervous System



With citalopram working against the regular nervous system processes, many of its withdrawal symptoms are directed into these sensory channels. Owing to of this, you may experience a dearth of usual body grouping that can lead to loss of your balance. Lightheaded touch due to privation of oxygen in the brain may cause you to go unconscious and fall.









Migraines or dull to sharp persistent pain in the head can also be practical.



Muscular tone and contractions will be affected, too. You will exhibit crazy tightening of muscles that can cause restless leg, twitching, tics and tremor. Wild trembling and shaking as if you are cold and chilled is also a symptom.



3. Citalopram Withdrawal Symptoms Involving the Cardiovascular



When withdrawing from citalopram abruptly, unusual or abnormal heart palpitations can be experienced. Your heartbeat is sometimes irregular but remains a rapid, forceful thump or flutter. An variety in the rhythm of your heart can also lead to symptoms of bradycardia or tachycardia. Bradycardia is when the heart percentage of an adult is slowed to beneath 60 beats per minute, because tachycardia is an increase of more than 100 beats per minute. Normal heart percentage is between 60 to 100 beats per minute.



An increase in blood consternation may also evince. When not taken early, this can damage your heart, brain, eyes, and kidneys or will lead to stroke and kidney failure.



4. Citalopram Withdrawal Symptoms Involving the Digestive System



The function of your gastrointestinal territory may also be disrupted with citalopram withdrawal. Nimble, severe, and painful cramps of the muscles in your belly will be privy. Bowel movements may be tough or quite frequent and excessive. Belching and bloating are also possible.



Nausea, innate throwing up, indigestion, heartburn, swallowing difficulty, gastroesophageal reflux and hemorrhoids are also in the index.



5. Citalopram Withdrawal Symptoms Involving Psychiatric Disorders



Mental and emotional balance will also be affected if you suddenly withdraw from citalopram use. You may lose a sense of place time and personal specification. Depression & anxiety symptoms may also worsen. Anxiety attacks can occur causing intense feelings of fear, dread, heart palpitations, insufficiency of breath, trembling, and tepid. You may also appearance symptoms of assault, irritation, agitation and nervousness. You may also give in to unusual fits of weeping for no apparent ground. Feelings of mistake, tribulation and loss will be aggravated to thoughts of suicide and finis.



Based on the symptoms of citalopram withdrawal inured, it can be very unpleasant and sometimes deadly. Abruptly discontinuing the use of this drug can lead to the extensive - mentioned manifestations. To avoid these, you must follow your doctor’ s method. Tapering the dose and carefully discontinuing the drug will help lessen your withdrawal discomforts.

Wednesday, February 4, 2015

TCM Treatment of Polycystic Ovary Syndrome ( PCOS )




Western View



TCM Pathology



Pattern Differentiations



Research



References



Western View



Polycystic ovary syndrome ( PCOS ) is a luteal transaction defect typified by anovulation, hyperandrogenism, insulin resistance and obesity. It affects 5 - 10 % of women.



PCOS is often exceptional as several small cysts located within the ovaries and chronic blunder to ovulate. PCOS repeatedly occurs with one or more of the following factors:



• Unprosperous estrogen misbalancing the hypothalamus - pituitary - ovarian ( HPO ) pivot.



• Imbalances in sugar metabolism and insulin levels.



• A tendency for diabetes.



• Obesity.



• Increased lipid levels.



• Higher prolactin levels.



PCOS involves a privation of communication between the gonadotropin releasing hormones and hormones of the hypothalamus and pituitary glands. A dysfunction of the endocrine and metabolic systems generally results in a poor response to hormone stimulating fertility drugs. Many PCOS patients resist ovulation stimulating drugs, which hyperstimulate the ovaries and create a multitude of side effects.



Typically, the ovaries are much larger than average, with multiple rows of cysts, unseen with a thick, slimy, waxy or hard apparent coating. These cysts produce male hormones that block follicles, causing them to degenerate. An overproduction of estrogen or an increase in insulin levels can cause androgen factors, like high testosterone, which in turn causes accidental body or facial hair or a thinning hairline.



The HPO focus affected with too much estrogen and not enough progesterone raises the luteinizing hormone ( LH ) and testosterone. Western diagnoses evaluate via ultrasound and blood tests for LH, follicle stimulating hormones ( FSH ) and testosterone. It is possible to have either long cycles with heavy blue or no ovulation or light cycles with little downbeat.



PCOS can combine menstrual disorders such as amenorrhea, oligomenorrhea, counterproductive uterine put away, infertility, hirsutism, and obesity. The uterine lining fails to shed each month, thereby increasing the possibility of endometrial cancer. Western treatment includes such medications as:



• Clomid to promote ovulation.



• Gonal - F or Pergonal ( gonadotropins ).



• Human chorionic Gonadotropin ( hCG ).



• Gluchophage, Metformin or Actos to subordination insulin resistance.



• Steroids to balance the androgen hormonal effects, which, over the long term, can cause liver damage and a reduction of bone density.



TCM Pathology



PCOS is a Yang disorder with imbalances intriguing the second half of the menstrual cycle. Involved organ systems number among the Spleen, Lungs, Liver and the Kidneys. Generally, PCOS derives from a deficiency of Kidney Yang, in its inability to transform, transport and evaporate fluids in the lower body. The accumulation of water in the pelvic cavity enlarges the ovaries, leading to Phlegm / Dampness or Blood stagnation.



Marking Differentiations



Phlegm / Dampness:



• Amenorrhea, light periods or infertility.



• A need to frequently “ clear your throat, ” which is caused by stress or emotions.



• Abdominal fullness or distention.



• Joint inflammation or aching.



• Heaviness in the chest, intestines area or body in general.



• Motility sleepy or laggard after a meal.



• Obesity.



• Hirsutism.



• Sinus congestion, lipomas, yeast infections or excessive vaginal discharge.



• Diarrhea or foul smelling stools ( indicates heat ).



• Mucus - like menstrual blood or stools.



• Colourless, swollen tongue body.



• White and sticky or greasy tongue coating.



• Weak or slippery pulse.



Blood stagnation:



• Amenorrhea, light periods, infertility.



• Heaviness, discomfort or pain in the chest or intestines.



• Excessive vaginal discharge.



• Hirsutism.



• Colourless - sensual or bluish - mature, swollen tongue body.











• Sticky, white tongue coating.



Research



Stenor - Victorin ( 2000 ) regulated ovulation in rats with electro - acupuncture ( EA ). This study proved that EA inhibits the hyperactivity of the sympathetic nervous system. Chen ( 1997 ) showed that acupuncture normalized dysfunction of the hypothalamus - pituitary - ovarian ( HPO ) fulcrum, and that EA may promote the exertion of the body and wisdom sensitive mechanisms normalizing GnRH, LH, and estrogen.



The friendly nervous system ( SNS ) is one of three parts of the autonomic nervous system. It mobilizes the body’ s skin under stress and is constantly active at a basal level to maintain homeostasis. It is duty-bound for the up and down regulating of many of the homeostatic mechanisms. Fibers from the SNS instigate nearly every organ system from L - 2 girl - 2. It provides very various regulatory functions gracious the ovaries, adrenals, pancreas, liver, and the endocrine system. The longitudinal organizations of the meridians such to L - 2 to T2 help you cognize why acupuncture is so effective in inhibiting this major nerve system. There is a correspondence between the SNS, segmental neural structures, the matching vessels, and nodal pathways. The Kidney, Liver, Heart, and Brain ( HPO ) systems like now affect the SNS. This may partially decipher why EA is so effective in treating PCOS. The ability to hushed the SNS, and ajar up the flow of Qi and Blood through these acupuncture meridians, resolves pathology that Western medicine can’ t somewhere comprehend.



Yoshimoto ( 1989 ) used the Chinese herbal formula, “ Wen Jing Tang” in a combined gonadotropin therapy resulting in ovulation in 43. 8 % of cases without ovarian awakened - stimulation. Wen Jing Tang is a formula used in cases of Deficiency and Cold in the Conception and Penetrating vessels; with stasis, and slight yin deficiency. It countered the effects of the Western medications resulting in ovulation.



Useful Acupuncture Points



Lu 7 ( R ) and K6 ( L ) regulate the Ren, HPO spindle, strengthen the Uterus and dissolve population. SP 6 connects the three Yin channels ( Liver, Kidney, Spleen ). Du 4 is the “ life gate” equated with the womb and useful in treating leucorrhea. Sp 9 is the water point on the Spleen channel. These points treat Kidney Yang deficiency leading to phlegm dampness.



Lu 7 and Ki 6 are also used for Blood stasis, in that they open the Ren and regimentation water balance. St 29, Sp10, and UB 17 are useful for all Blood issues. Lv 14 treats dormant Qi.



References



Cai, Buss. ( 1997 ). Substitution of acupuncture for HCG in ovulation induction. Chronicle of Standard Chinese Medicine, 17 ( 2 ), 119 - 121.



Chen, B. Y. ( 1997 ). Acupuncture normalizes dysfunction of hypothalamic - pituitary - ovarian spindle. Acupuncture & Electro - therapeutics Resources. International Notebook, 22 ( 2 ), 97 - 108.



Stener - Victorin, E., Lundeberg, T., Waldenstrom, U., Manni, L., Aloe, L., Gunnarsson, S., et al. ( 2000 ). Effects of electro - acupuncture on nerve growth factor and ovarian morphology in rats with experimentally induced polycystic ovaries. Biology of Reproduction, 63, 1497 - 1503.



Stener - Victorin, E., Waldenstrom, U., Anderson, S., & Wikland, M. ( 1996 ). Reduction of blood flow impedance in the uterine arteries of infertile women with electro - acupuncture. Human Reproduction, 11, 1314 - 1317.



Yoshimoto, Y., Miyake, A., Tasaka, K., Aono, T., & Tanizawa, O. ( 1989 ). Ovulation following combined therapy with wen - jing - tang and clomiphene citrate therapy in anovulatory women. American Daybook of Chinese Medicine, 17, 243 - 244.